Author

E. Yakubovich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. A. Schaffer· 1 shared A. Buchler· 1 shared A. Hagerman· 1 shared A. Satpathy· 1 shared B. Rotstein· 1 shared B. Vanderhyden· 1 shared C. Fong-McMaster· 1 shared C. Tanese De Souza· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. A. Schaffer

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2 papers

Recent·Most cited

Temporal genomic analysis of melanoma rejection identifies regulators of tumor immune evasion

S. C. Shvefel, J. Pai, Y. Cao, L. Pal, R. Levy, W. Yao, K. Cheng, M. Zemanek, O. Bartok, C. Weller, Y. Yin, P. Du, E. Yakubovich, I. Orr, S. Ben-Dor, , Y. Samuels

The paper identifies Mif as a regulator of tumor immune evasion in low intra-tumor heterogeneity melanoma by analyzing single-cell RNA sequencing data and validating in patient data.

bioRxiv · Nov 29, 2023 · PreprintCancer Biology

More than a ligand: PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I interferon pathway.

J. Hodgins, J. Abou-Hamad, A. Hagerman, E. Yakubovich, C. Tanese De Souza, M. Marotel, A. Buchler, S. Fadel, M. Park, C. Fong-McMaster, M. J. F. Crupi, J. C. Bell, M.-E. Harper, B. Rotstein, R. Auer, , M. Ardolino

PD-L1 promotes oncolytic virus infection by inhibiting the type I interferon pathway through a metabolic shift involving enhanced glycolysis and lactate production.

bioRxiv · Aug 31, 2022 · PreprintCancer Biology