Author

Edel M. McCrea

Stanford Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Laura Donatella AttardiiD· 2 shared Mengxiong WangiD· 2 shared Aicha R. Mabene· 1 shared Alexandros P. DrainasiD· 1 shared Anthony M. Boutelle· 1 shared Brooke E. HowittiD· 1 shared Brooks A. BenardiD· 1 shared David YaoiD· 1 shared

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2025-2025 · peak 2/yr

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10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Laura Donatella AttardiORCID

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2 papers

Recent·Most cited

Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network

Anthony M. Boutelle, Aicha R. Mabene, David Yao, Haiqing Xu, Mengxiong Wang, Yuning J. Tang, Steven S. Lopez, Sauradeep Sinha, János Demeter, Ran Cheng, Brooks A. Benard, Edel M. McCrea, Liz J. Valente, Alexandros P. Drainas, Martin Fischer, , Laura Donatella Attardi

The paper identifies ZMAT3 and CDKN1A as key hubs in the p53 tumor suppression network through integrative multiomic analyses in a mouse model.

Cell Death and Differentiation · Apr 22, 2025Peer-reviewedCancer Biology

Ptpn14 Knockout Mice Reveal Critical Female-Specific Roles for the Hippo Pathway

Edel M. McCrea, Neoklis Makrides, Takako Tabata, Hannes S. Vogel, Brooke E. Howitt, Wencke Reineking, José G. Vilches-Moure, Mengxiong Wang, Xin Zhang, Laura Donatella Attardi

This study shows that Ptpn14 deficiency in mice causes female-specific Hippo pathway defects, including corneal lesions, uterine defects, and organ abnormalities, with conserved roles in humans.

bioRxiv · Jan 13, 2025 · PreprintDevelopmental Biology