Author

Eike C. Struck

UiT The Arctic University of Norway

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Christopher Florian HolteiD· 2 shared Karolina SzafranskaiD· 2 shared Bartłomiej ZapotocznyiD· 1 shared Basema Abujayyab· 1 shared Cecilia LindskogiD· 1 shared Dina Spigseth Hovland· 1 shared Fredrik PonténiD· 1 shared Gianina Dumitriu· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

Christopher Florian HolteORCID

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3 papers

Recent·Most cited

Long-term 2D monoculture of primary mouse LSEC preserves scavenging capacity and enables siRNA knockdown of Mrc1

Karolina Szafranska, Basema Abujayyab, Eike C. Struck, Dina Spigseth Hovland, Christopher Florian Holte, Gianina Dumitriu, Karen Kristine Sørensen, Peter McCourt

This study develops a 2D monoculture method to maintain primary mouse LSEC viability and endocytic function for 10 days, enabling siRNA knockdown of Mrc1.

bioRxiv · May 7, 2026 · PreprintCell Biology

Hydrogen peroxide damage to scavenging function and ultrastructure of liver sinusoidal endothelial cells is prevented by n-acetyl-cysteine but not GSH

Larissa D. Kruse, Christopher Florian Holte, Bartłomiej Zapotoczny, Eike C. Struck, Jasmin Schürstedt, Wolfgang Hübner, Thomas R. Huser, Karolina Szafranska

This study shows that hydrogen peroxide damages liver sinusoidal endothelial cells, reducing their scavenging function and causing structural changes, which can be mitigated by N-acetyl-cysteine but not glutathione.

Hepatology Communications · Jan 15, 2025Peer-reviewedCell Biology

A tissue centric atlas of cell type transcriptome enrichment signatures

Philip Dusart, Sofia Öling, Eike C. Struck, Marthe Norreen-Thorsen, Martin Zwahlen, Kalle von Feilitzen, Per Oksvold, Martina Bosić, MJ Iglesias, Thomas Renné, Jacob Odeberg, Fredrik Pontén, Cecilia Lindskog, Mathias Uhlén, Lynn M. Butler

The paper generates a tissue-specific cell type enrichment atlas using bulk RNAseq data from 15 human organs, identifying lowly expressed genes and shared gene signatures across cell types.

bioRxiv · Jan 10, 2023 · PreprintSystems Biology