Hydrogen peroxide damage to scavenging function and ultrastructure of liver sinusoidal endothelial cells is prevented by n-acetyl-cysteine but not GSH
Larissa D. Kruse, Christopher Florian Holte, Bartłomiej Zapotoczny, Eike C. Struck, Jasmin Schürstedt, Wolfgang Hübner, Thomas R. Huser, Karolina Szafranska
This study shows that hydrogen peroxide damages liver sinusoidal endothelial cells, reducing their scavenging function and causing structural changes, which can be mitigated by N-acetyl-cysteine but not glutathione.
Hepatology Communications · Jan 15, 2025Peer-reviewedCell Biology