Peter McCourt

This study examines how polypharmacy affects liver sinusoidal endothelial cells, showing drug- and concentration-dependent changes in fenestrations and endocytosis.

This study develops a 2D monoculture method to maintain primary mouse LSEC viability and endocytic function for 10 days, enabling siRNA knockdown of Mrc1.

This paper investigates how fenofibrate and its metabolite fenofibric acid affect liver endothelial permeability, finding fenofibrate reduces fenestration and mechanical properties while fenofibric acid does not.