Molecular BiologyNature AgingPeer-reviewed
In vivo reprogramming leads to premature death due to hepatic and intestinal failure.
Alberto Parras, Alba Vílchez-Acosta, Gabriela Desdín-Micó…·Alejandro Ocampo
This study shows that continuous in vivo reprogramming with OSKM causes hepatic and intestinal failure, leading to premature death, but a new mouse strain reduces these effects.
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