Reproductive state controls transcription in the murine liver, with implications for breast cancer liver metastasis
Michelle K. Ozaki, Yi Zhang, Alexandra Q. Bartlett, Elise de Wilde, Xiangnan Guan, Alex M. Yang, Zheng Xia, Pepper S. Schedin
This study examines liver transcriptional changes during lactation and weaning in mice, finding similarities between liver involution and pre-metastatic niches, with implications for breast cancer metastasis.
Proceedings of the National Academy of Sciences · Jun 11, 2025Peer-reviewedCancer Biology