Courtney B. Betts

Myc and Kras cooperate in adult acinar cells to drive phenotypic heterogeneity, metastasis, and therapeutic resistance in a novel pancreatic cancer mouse model

This study develops a novel pancreatic cancer mouse model by expressing Myc and mutant Kras in adult acinar cells, showing metastasis and therapeutic resistance similar to human PDAc.

Altered liver metabolism post-wean abolishes efficacy of vitamin D for breast cancer prevention in a mouse model

This study shows that vitamin D's anti-cancer effects are reduced in post-wean mice due to altered liver metabolism, highlighting the importance of reproductive history in treatment efficacy.

Alignment, Segmentation and Neighborhood Analysis in Cyclic Immunohistochemistry Data Using CASSATT

CASSATT processes cycIHC data to align images, segment nuclei, and analyze spatial cell interactions and neighborhoods.

MCMICRO: A scalable, modular image-processing pipeline for multiplexed tissue imaging

MCMICRO processes multiplexed tissue images into single-cell data, demonstrating its versatility across different tissues and imaging platforms.