Author

Michelle K. Ozaki

Oregon Health & Science UniversityORCID 0000-0002-3356-9071Unclaimed ORCID profile · follow to get notified of new preprints

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Cancer Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Elise de Wilde· 2 shared Pepper S. SchediniD· 2 shared Zheng XiaiD· 2 shared Abigail L. LibertyiD· 1 shared Alex M. YangiD· 1 shared Alexandra Q. BartlettiD· 1 shared Andrea E. DeBarberiD· 1 shared Courtney B. BettsiD· 1 shared

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2024-2025 · peak 1/yr

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10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Elise de Wilde

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2 papers

Recent·Most cited

Reproductive state controls transcription in the murine liver, with implications for breast cancer liver metastasis

Michelle K. Ozaki, Yi Zhang, Alexandra Q. Bartlett, Elise de Wilde, Xiangnan Guan, Alex M. Yang, Zheng Xia, Pepper S. Schedin

This study examines liver transcriptional changes during lactation and weaning in mice, finding similarities between liver involution and pre-metastatic niches, with implications for breast cancer metastasis.

Proceedings of the National Academy of Sciences · Jun 11, 2025Peer-reviewedCancer Biology

Altered liver metabolism post-wean abolishes efficacy of vitamin D for breast cancer prevention in a mouse model

Sarah M. Bernhardt, Michelle K. Ozaki, Courtney B. Betts, Lisa A. Bleyle, Andrea E. DeBarber, Jaime Fornetti, Abigail L. Liberty, Elise de Wilde, Yi Zhang, Zheng Xia, Pepper S. Schedin

This study shows that vitamin D's anti-cancer effects are reduced in post-wean mice due to altered liver metabolism, highlighting the importance of reproductive history in treatment efficacy.

bioRxiv · May 28, 2024 · PreprintCancer Biology