Author

Elizabeth Pyman

NIHR Imperial Biomedical Research Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Reed· 1 shared Alison E. JohniD· 1 shared Ann SaadaiD· 1 shared Bin LiuiD· 1 shared Brendan James BattersbyiD· 1 shared Christopher Benjamin JacksoniD· 1 shared Christopher J. CarrolliD· 1 shared Diego BalboaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

A. Reed

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Author profile →

2 papers

Recent·Most cited

Targeting AKAP13 RhoGEF activity ameliorates pro-fibrotic phenotypes driven by the IPF associated AKAP13 risk variant

Bin Liu, James Michael May, Greg Contento, Sara Gangi, Louise A. Organ, Elizabeth Pyman, Iyobel Kibreab, Lan Zhao, Huayang Yao, Rachel Clare Chambers, Iain D. Stewart, A. Reed, Gisli R. Jenkins, Alison E. John

This study shows that an AKAP13 genetic variant promotes fibrosis by altering epithelial signaling, and inhibiting AKAP13's RhoGEF activity reduces fibrotic markers in IPF models.

bioRxiv · Jan 23, 2026 · PreprintGenetics

Supernumerary proteins of the human mitochondrial ribosomal small subunit are integral for assembly and translation

Taru Hilander, Ryan Awadhpersad, Geoffray Monteuuis, Krystyna L. Broda, Max Pohjanpelto, Elizabeth Pyman, Sachin Kumar Singh, Tuula A. Nyman, Isabelle M.-T.C. Crevel, Robert William Taylor, Ann Saada, Diego Balboa, Brendan James Battersby, Christopher Benjamin Jackson, Christopher J. Carroll

The paper investigates the functional roles of 14 unique human mitochondrial ribosomal proteins in the small subunit, showing their essentiality in assembly and translation, with a redox-regulated role for mS37.

iScience · Jun 5, 2024Peer-reviewedMolecular Biology