Tissue-specific consequences of tag fusions on protein expression in transgenic mice
Gillian C.A. Taylor, Lewis Macdonald, Natalia A. Szulc, Evelina Gudauskaite, Brianda Areli Hernández-Morán, Jennifer Margaret Brisbane, Molly Donald, Ella Taylor, Dejin Zheng, Bin Gu, Pleasantine Mill, Patricia Levy Yeyati, Wojciech Pokrzywa, Claudia Ribeiro de Almeida, Andrew J. Wood
The paper shows that tag fusions can have tissue-specific effects on protein stability in transgenic mice, depending on the cell and tissue environment.
PLoS Genetics · Aug 25, 2025Peer-reviewedMolecular Biology