Author

Elmar Nurmemmedov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:structural biology· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Raymond K. Yengo· 2 shared Alexandra McMellen· 1 shared Benjamin G. Bitler· 1 shared Diana M. CittellyiD· 1 shared George-Lucian MoldovaniD· 1 shared Heidi Wilson· 1 shared Hyunmin Kim· 1 shared Jennifer Aguilera· 1 shared

Activity by Year

2018-2018 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiophysics

Raymond K. Yengo

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Author profile →

3 papers

Recent·Most cited

Targeting Wnt Signaling To Overcome PARP Inhibitor Resistance

Tomomi M. Yamamoto, Alexandra McMellen, Zachary L. Watson, Jennifer Aguilera, Matthew J. Sikora, Rebecca Ferguson, Elmar Nurmemmedov, Tanay Thakar, George-Lucian Moldovan, Hyunmin Kim, Diana M. Cittelly, Heidi Wilson, Kian Behbakht, Benjamin G. Bitler

This study identifies Wnt signaling activation as a mechanism of PARP inhibitor resistance in HGSOC and shows that combining PARPi with Wnt inhibitors reduces tumor burden.

bioRxiv · Jul 27, 2018 · PreprintCancer Biology

Structural view on the role of WT1’s zinc finger 1 in DNA binding

Raymond K. Yengo, Elmar Nurmemmedov, Marjolein M Thunnissen

This paper presents X-ray structures of WT1 zinc fingers 1-3 bound to DNA, showing zinc finger 1 lacks DNA binding specificity and only contributes modestly to DNA binding affinity.

bioRxiv · Mar 18, 2018 · PreprintBiophysics

Structure of WT1 zinc fingers bound to its cognate DNA: Implications of the KTS insert

Raymond K. Yengo, Elmar Nurmemmedov, Marjolein M.G.M. Thunnissen

This study presents the crystal structures of WT1 zinc fingers with and without the KTS insert bound to DNA, revealing how the KTS affects DNA binding without altering specificity.

bioRxiv · Mar 18, 2018 · PreprintBiophysics