A circular engineered sortase for interrogating histone H3 in chromatin
Samuel D. Whedon, Kwangwoon Lee, Zhipeng A. Wang, Emily Zahn, Congcong Lu, Maheeshi Yapa Abeywardana, Louise Fairall, Eunju Nam, Sarah E. DuBois-Coyne, Pablo De Ioannes, Xinlei Sheng, Adelina Andrei, Emily Lundberg, Jennifer Jiang, Karim‐Jean Armache, , Philip A. Cole
This paper introduces an engineered sortase, cW11, for modifying and isolating histone H3 tails to study epigenetic modifications and their effects on enzyme processing and protein recognition.
Journal of the American Chemical Society · Nov 25, 2024Peer-reviewedBiochemistry