Author
Brigham and Women's HospitalORCID 0000-0002-3745-5645Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Farzad Yousefi, Eric Simental, Yongming Du…·Bassem Al‐Sady
This paper investigates the G9a-GLP heterodimer's feedback mechanism, showing that both ANK domains are required for H3K9 dimethylation and nucleosome binding, suggesting intranucleosomal feedback.
Mina Masoumeh Tayari, Helena Gomes Dos Santos, Sadat Dokaneheifard…·Ramin Shiekhattar
The paper shows that Corin, a dual LSD1/CoREST inhibitor, synergizes with ATRA to induce differentiation and apoptosis in AML by disrupting CoREST-RAR/RXR complexes and recruiting p300.
Samuel D. Whedon, Kwangwoon Lee, Zhipeng A. Wang…·Philip A. Cole
This paper introduces an engineered sortase, cW11, for modifying and isolating histone H3 tails to study epigenetic modifications and their effects on enzyme processing and protein recognition.