Author

Emma J. Laurence

Lawrence Livermore National Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Organism:E. coli· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Chao LiuiD· 3 shared Matthew A. ColemaniD· 3 shared Steven A. Hoang-PhouiD· 3 shared Ted A. LaurenceiD· 3 shared Shakiba Nikfarjam· 2 shared Adam N. Laurence· 1 shared B. Dillon Vannest· 1 shared Congwang Ye· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersBiophysics

Chao LiuORCID

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3 papers

Recent·Most cited

Fluorescence correlation spectroscopy measurements of the chlamydia outer protein B (CopB) made by cell-free protein synthesis

Emma J. Laurence, Shakiba Nikfarjam, Steven A. Hoang-Phou, Ted A. Laurence, Matthew A. Coleman, Chao Liu

The paper uses fluorescence correlation spectroscopy to analyze YFP-CopB production in cell-free synthesis, measuring its concentration, size, and maturation.

bioRxiv · Jun 10, 2026 · PreprintBiophysics

Rapid Antibody Fragment Production and Binding Analysis Using Cell-Free Protein Synthesis Combined with Fluorescence Correlation Spectroscopy

Shakiba Nikfarjam, Chao Liu, Emma J. Laurence, Adam N. Laurence, Jennifer L. Chlebek, Dante P. Ricci, Steven A. Hoang-Phou, Ted A. Laurence, Matthew A. Coleman

This paper develops a cell-free protein synthesis method combined with FCS to rapidly produce and characterize antibody fragments, showing improved solubility and binding analysis.

bioRxiv · Aug 5, 2025 · PreprintBiophysics

Real-time affinity measurements of proteins synthesized in cell-free lysate using fluorescence correlation spectroscopy

Chao Liu, Steven A. Hoang-Phou, Congwang Ye, Emma J. Laurence, Matthew J. Laurence, Erika J. Fong, Nikki M. Hammond, B. Dillon Vannest, Nicholas N. Watkins, Ted A. Laurence, Matthew A. Coleman

This paper develops a method to measure protein-protein interactions in real-time using cell-free synthesis and fluorescence correlation spectroscopy, achieving high sensitivity and throughput.

Analytical Chemistry · Apr 30, 2025Peer-reviewedBiophysics