Author

Eric Purisic

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Jinye DaiiD· 2 shared Christian Valade· 1 shared Cong XiaoiD· 1 shared Darielle Lewis-SandersiD· 1 shared Devin RocksiD· 1 shared Eduardo F. GalloiD· 1 shared Eric Sobie· 1 shared Heining ChamiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Jinye DaiORCID

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3 papers

Recent·Most cited

GluD1 Modulates GluN2B-containing NMDAR Function and Plasticity at Subicular Synapses

Eric Purisic, Darielle Lewis-Sanders, Marian Zhong, Joshua Stamos, Tianhua Wang, Christian Valade, Markus Wöhr, Eric Sobie, Jinye Dai

This study shows GluD1 is essential for maintaining GluN2B-containing NMDAR function, synaptic plasticity, and memory, with implications for neuropsychiatric disorders.

bioRxiv · Aug 19, 2026 · PreprintNeuroscience

Egr1 is a sex-specific regulator of neuronal chromatin, synaptic plasticity, and behaviour

Devin Rocks, Luisa Demarchi, Laila Ouldibbat, Eric Purisic, Heining Cham, Eduardo F. Gallo, John M. Greally, Masako Suzuki, Marija Kundaković

This study shows that Egr1 overexpression induces sex-specific changes in neuronal chromatin, gene expression, and behavior in female rodents, mimicking high-oestrogenic phases and affecting hormone-depleted females.

Nature Communications · Dec 13, 2025Peer-reviewedNeuroscience

Bipolar and schizophrenia risk gene AKAP11 encodes an autophagy receptor coupling the regulation of PKA kinase network homeostasis to synaptic transmission

You-Kyung Lee, Cong Xiao, Xiaoting Zhou, Leo L. Wang, Meghan G. McReynolds, Zhiping Wu, Xian Han, Eric Purisic, Henry Kim, Xianting Li, Zhiping P. Pang, Jinye Dai, Junmin Peng, Nan Yang, Zhenyu Yue

This study identifies AKAP11 as a critical autophagy receptor linking PKA kinase network regulation to synaptic transmission, with loss-of-function impacting pathways associated with bipolar disorder and schizophrenia.

Nature Communications · Nov 28, 2025Peer-reviewedNeuroscience