High content screening and computational prediction reveal viral genes that suppress innate immune response
Tai L. Ng, Erika J. Olson, Tae Yeon Yoo, H. Sloane Weiss, Yukiye Koide, Peter David Koch, Nathan J. Rollins, Pia Mach, Tobias Meisinger, Trenton Bricken, Timothy Z. Chang, Colin Molloy, Jérôme Zürcher, Roger L. Chang, Timothy John Mitchison, , Pamela A. Silver
The paper develops a high-content assay to identify viral genes that suppress innate immunity and validates known and novel immune suppressors from various viral families.
mSystems · Mar 23, 2022Peer-reviewedSystems Biology