A Perturb-seq screen guided by species divergence uncovers pathways for collateral artery formation
Xiaochen Fan, Ronghao Zhou, Brian C. Raftrey, Pamela E. Rios Coronado, Emily Trimm, Erin Clancy, Xinhong Chen, Jamie Bozeman, Maggie S. Chen, Shoxruxxon Alimukhamedov, Juan Alcocer, Idalina Bonham, Stuti Agarwal, Alina Isakova, Vinicio de Jesús Pérez, , Kristy Red‐Horse
The paper uses Perturb-seq in mice to identify genes that promote collateral artery formation by comparing gene expression between guinea pigs and mice.
bioRxiv · May 10, 2026 · PreprintDevelopmental Biology