Structure and mechanism of the RalGAP tumor suppressor complex
René Rasche, Björn Udo Klink, Lisa Helene Apken, Esther Michalke, Minghao Chen, Andrea Oeckinghaus, Christos Gatsogiannis, Daniel Kümmel
This study presents the cryo-EM structure of the RalGAP tumor suppressor complex, revealing its tetrameric architecture and providing insights into its function and relevance in cancer.
Nature Communications · Jul 30, 2025Peer-reviewedBiochemistry