René Rasche

This paper computationally designs light-responsive proteins that undergo conformational changes upon light activation, enabling precise control of biological functions.

This study presents the cryo-EM structure of the RalGAP tumor suppressor complex, revealing its tetrameric architecture and providing insights into its function and relevance in cancer.

The paper presents the first crystal structure of a cis-COM domain in NRPSs and shows its role in scaffolding domain architecture for efficient peptide synthesis.