ImmunologybioRxivPreprint
Mechanistic basis for nigericin-induced NLRP1 inflammasome activation in human epithelial cells
Pritisha Rozario, Miriam Pinilla, Anna Constance Vind…·Franklin Zhong
This study identifies the mechanism by which nigericin activates the NLRP1 inflammasome in human epithelial cells through potassium efflux and ribotoxic stress response.
DOI 10.1101/2023.06.23.546021