The small membrane protein YohP induces membrane depolarization and ppGpp accumulation in Escherichia coli.
Ana Natriashvili, Nahid Mohammadsadeghi, Martin Milanov, Eva Smudde, Isabel Prucker, Henning Jacob Jessen, Iulia Carabadjac, Heiko H. Heerklotz, Pedro Henrique Cavalcanti Franco, Julian D. Langer, Hans‐Georg Koch
This study identifies YohP as a small membrane protein in E. coli that induces membrane depolarization and (p)ppGpp accumulation, leading to metabolic silencing under stress.
bioRxiv · May 6, 2025 · PreprintMicrobiology