Pedro Henrique Cavalcanti Franco

Breaking new ground into RAD51-BRC repeats interplay in Homologous Recombination

This study investigates the RAD51-BRC repeats interaction using computational and experimental methods to better understand its role in homologous recombination and its implications for cancer.

The small membrane protein YohP induces membrane depolarization and ppGpp accumulation in Escherichia coli.

This study identifies YohP as a small membrane protein in E. coli that induces membrane depolarization and (p)ppGpp accumulation, leading to metabolic silencing under stress.

Integrating computational and experimental biophysics reveals novel insights into the RAD51-BRC4 interaction

This study combines computational and experimental methods to characterize the conformational dynamics of the RAD51-BRC4 complex, revealing key residues involved in their interaction.

Magnesium Transporter MgtA revealed as a Dimeric P-type ATPase

The paper reports the first structure of the Mg2+ transporter MgtA using cryo-EM, revealing its dimeric form and mechanism of Mg2+ transport.