Author

Evan Cao

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Carina SeahiD· 2 shared Eli A. StahliD· 2 shared Jessica JohnsoniD· 2 shared Judit García‐GonzáleziD· 2 shared Kayla G. TownsleyiD· 2 shared Kristen BrennandiD· 2 shared Laura M. HuckinsiD· 2 shared Nadine SchrodeiD· 2 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Carina SeahORCID

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2 papers

Recent·Most cited

Non-additive effects of schizophrenia risk genes reflect convergent downstream function

PJ Michael Deans, Carina Seah, Jessica Johnson, Judit García‐González, Kayla G. Townsley, Evan Cao, Nadine Schrode, Eli A. Stahl, Paul F. O’Reilly, Laura M. Huckins, Kristen Brennand

The paper shows that non-additive effects of schizophrenia risk genes are due to convergent downstream transcriptomic effects and sub-additive changes, suggesting functional redundancy as a mechanism for non-additivity.

medRxiv · Mar 20, 2023 · PreprintGenetic & Genomic Medicine

Convergent and non-additive impact of schizophrenia risk genes in human neurons

PJ Michael Deans, Kayla G. Townsley, Aiqun Li, Carina Seah, Jessica Johnson, Judit García‐González, Evan Cao, Nadine Schrode, Alex Yu, Sam Cartwright, Georgios Voloudakis, Wen Zhang, Minghui Wang, John F. Fullard, Kiran Girdhar, , Kristen Brennand

This study shows that schizophrenia risk genes have convergent and non-additive transcriptomic effects when perturbed together in human neurons, suggesting functional redundancy and complex interactions.

bioRxiv · Mar 29, 2022 · PreprintNeuroscience