Nadine Schrode

This study shows HIV transcription spans a continuum in human lymphoid tissue, linking viral burden to host-cell biology and suggesting persistent viral activity reflects a spectrum of host-virus states.

This study uses deep learning and reference atlases to analyze tumor cell populations in mouse bladder cancer, identifying lineage-specific subpopulations and their therapeutic vulnerabilities.

The paper shows that non-additive effects of schizophrenia risk genes are due to convergent downstream transcriptomic effects and sub-additive changes, suggesting functional redundancy as a mechanism for non-additivity.

This study shows that schizophrenia risk genes have convergent and non-additive transcriptomic effects when perturbed together in human neurons, suggesting functional redundancy and complex interactions.

The paper uses single-cell RNA sequencing to study atrial and ventricular myocardial cell differentiation, identifying lineage trajectories and effects of retinoic acid on cardiac development.

The paper extends the RiboTag system for cell-type specific RNA depletion in vitro, showing variable efficiency across replicates.

This study identifies molecular networks and key regulators in Alzheimer’s Disease using integrative genomics and experimental validation.