Author

F. C. Motta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

A. C. D. Paixao· 2 shared E. Delatorre· 2 shared G. Bello· 2 shared L. Appolinario· 2 shared M. M. Siqueira· 2 shared P. C. Resende· 2 shared S. B. Fernandes· 2 shared T. Graf· 2 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. C. D. Paixao

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A potential SARS-CoV-2 variant of interest (VOI) harboring mutation E484K in the Spike protein was identified within lineage B.1.1.33 circulating in Brazil

P. C. Resende, T. Graf, A. C. D. Paixao, L. Appolinario, R. S. Lopes, A. C. F. Mendonca, A. S. B. da Rocha, F. C. Motta, L. G. L. Neto, R. Khouri, C. I. de Oliveira, P. Santos-Muccillo, J. F. Bezerra, D. L. F. Teixeira, I. Riediger, , M. M. Siqueira

bioRxiv · Mar 12, 2021Microbiology

Large-scale design and refinement of stable proteins using sequence-only models

J. M. Singer, S. Novotney, D. Strickland, H. K. Haddox, N. Leiby, G. J. Rocklin, C. M. Chow, A. Roy, A. K. Bera, F. C. Motta, L. Cao, E.-M. Strauch, T. M. Chidyausiku, A. Ford, E. Ho, , E. Klavins

The paper presents two neural network models for predicting and generating stable proteins based on amino acid sequences, showing improved stability in both expert-designed and model-generated proteins.

bioRxiv · Mar 12, 2021Biophysics

Genomic surveillance of SARS-CoV-2 reveals community transmission of a major lineage during the early pandemic phase in Brazil

P. C. Resende, E. Delatorre, T. Graf, D. Mir, F. C. Motta, L. Appolinario, A. C. D. Paixao, M. Ogrzewalska, B. Caetano, M. C. Santos, J. A. Ferreira, E. C. Souza Junior, S. P. Silva, S. B. Fernandes, L. A. Vianna, , M. M. Siqueira

This study analyzes SARS-CoV-2 genetic diversity in Brazil during the early pandemic phase, identifying community transmission of a major lineage and its spread to other countries.

bioRxiv · Jun 17, 2020 · PreprintEvolutionary Biology

Reconciling Conflicting Models for Global Control of Cell-Cycle Transcription

C.-Y. Cho, F. C. Motta, C. M. Kelliher, A. Deckard, S. B. Haase

The paper challenges a recent conclusion that cell-cycle transcription is controlled by a CDK-APC/C oscillator, showing that TF networks also play a critical role.

bioRxiv · Mar 14, 2017Cell Biology