Author

M. M. Siqueira

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:human· 3 Organism:virus· 3 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:phylogenetics / evolution· 1 Approach:statistical model· 1

Frequent Co-Authors

P. C. Resende· 4 shared C. F. da Costa· 3 shared F. G. Naveca· 3 shared A. C. D. Paixao· 2 shared A. Flaxman· 2 shared A. J. Mentzer· 2 shared A. Pauvolid-Correa· 2 shared A. R. Matos· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

P. C. Resende

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

SARS-CoV-2 infection of human brain microvascular endothelial cells leads to inflammatory activation through NF-κB non-canonical pathway and mitochondrial remodeling

S. Torices, C. S. Motta, B. G. da Rosa, A. C. Marcos, L. Alvarez-Rosa, M. Siqueira, T. Moreno-Rodriguez, A. Matos, B. Caetano, J. Martins, E. Loiola, L. Gladulich, O. R. Bagshaw, J. A. Stuart, M. M. Siqueira, , D. Adesse

This study investigates SARS-CoV-2 infection of human brain microvascular endothelial cells, finding NF-κB non-canonical pathway activation and mitochondrial remodeling contribute to neuroinflammation and BBB disruption.

bioRxiv · Jun 16, 2022 · PreprintCell Biology

Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses

W. Dejnirattisai, J. Huo, D. Zhou, J. Zahradni_k, P. Supasa, C. Liu, H. M. E. Duyvesteyn, H. Ginn, A. J. Mentzer, A. Tuekprakhon, R. Nutalai, B. - Wang, A. Dijokaite, S. Khan, O. Avinoam, , Mad

This study shows that Omicron-B.1.1.529 has extensive mutations in Spike that reduce neutralization by antibodies from vaccinated and previously infected individuals, and escape most monoclonal antibodies.

bioRxiv · Dec 3, 2021 · PreprintMicrobiology

A potential SARS-CoV-2 variant of interest (VOI) harboring mutation E484K in the Spike protein was identified within lineage B.1.1.33 circulating in Brazil

P. C. Resende, T. Graf, A. C. D. Paixao, L. Appolinario, R. S. Lopes, A. C. F. Mendonca, A. S. B. da Rocha, F. C. Motta, L. G. L. Neto, R. Khouri, C. I. de Oliveira, P. Santos-Muccillo, J. F. Bezerra, D. L. F. Teixeira, I. Riediger, , M. M. Siqueira

bioRxiv · Mar 12, 2021Microbiology

Antibody evasion by the Brazilian P.1 strain of SARS-CoV-2

W. - Dejnirattisai, D. - Zhou, P. - Supasa, C. - Liu, A. J. Mentzer, H. M. Ginn, Y. - Zhao, H. M. E. Duyvesteyn, A. Tuekprakhon, R. Nutalai, B. - Wang, G. C. Paesen, C. - Lopez-Camacho, J. - Slon-Campos, T. Walter, , Barne

This study compares antibody resistance of SARS-CoV-2 variants P.1, B.1.351, and B.1.1.7, finding P.1 is less resistant to antibodies despite similar ACE2 binding mutations.

bioRxiv · Mar 12, 2021Microbiology

Atazanavir inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production

N. Fintelman-Rodrigues, C. Q. Sacramento, C. Ribeiro Lima, F. Souza da Silva, A. Ferreira, M. Mattos, C. S. de Freitas, V. Cardoso Soares, S. da Silva Gomes Dias, J. R. Temerozo, M. Miranda, A. R. Matos, F. A. Bozza, N. Carels, C. Roberto Alves, , T. M. L. Souza

This study shows that atazanavir inhibits SARS-CoV-2 replication and reduces pro-inflammatory cytokine production in vitro.

Antimicrobial Agents and Chemotherapy · Sep 21, 2020Peer-reviewedMicrobiology

Genomic surveillance of SARS-CoV-2 reveals community transmission of a major lineage during the early pandemic phase in Brazil

P. C. Resende, E. Delatorre, T. Graf, D. Mir, F. C. Motta, L. Appolinario, A. C. D. Paixao, M. Ogrzewalska, B. Caetano, M. C. Santos, J. A. Ferreira, E. C. Souza Junior, S. P. Silva, S. B. Fernandes, L. A. Vianna, , M. M. Siqueira

This study analyzes SARS-CoV-2 genetic diversity in Brazil during the early pandemic phase, identifying community transmission of a major lineage and its spread to other countries.

bioRxiv · Jun 17, 2020 · PreprintEvolutionary Biology

In Vitro Inhibition of SARS-CoV-2 Infection by Bovine Lactoferrin

C. A. M. Carvalho, A. R. Matos, B. C. Caetano, I. P. Sousa Junior, S. P. C. Campos, B. R. Geraldino, C. A. Barros, M. A. P. Almeida, V. P. Rocha, A. M. V. Silva, J. G. Melgaco, P. C. C. Neves, T. Azamor, A. P. D. Ano Bom, M. M. Siqueira, , R. B. Goncalves

This study investigates the antiviral effect of bovine lactoferrin against SARS-CoV-2 in vitro, showing significant reduction in viral yield in two cell lines.

bioRxiv · May 13, 2020 · PreprintMicrobiology