Author

F. J. Cimas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B. Belandia· 2 shared D. M. Fernandez-Aroca· 2 shared I. Andres· 2 shared M. j. Ruiz-Hidalgo· 2 shared N. Garcia-Flores· 2 shared P. Fernandez-Aroca· 2 shared R. Sanchez-Prieto· 2 shared s. sabater· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

B. Belandia

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The signaling axis CDK12-BRCA1 mediates dinaciclib associated radiosensitivity through p53-mediated cellular senescence.

N. Garcia-Flores, D. M. Fernandez-Aroca, C. Garnes Garcia, A. Dominguez-Calvo, s. sabater, I. Andres, J. Jimenez Suarez, P. Fernandez-Aroca, F. J. Cimas, G. de Carcer, B. Belandia, I. Palmero, P. Huertas, M. j. Ruiz-Hidalgo, R. Sanchez-Prieto

This paper shows dinaciclib increases radiosensitivity in some cancer cell lines by inhibiting CDK12, reducing BRCA1, and promoting p53-dependent senescence.

bioRxiv · Apr 25, 2024 · PreprintCancer Biology

MAPK11 (p38β) is a major determinant of cellular radiosensitivity by enhancing IR-associated senescence.

D. M. Fernandez-Aroca, N. Garcia-Flores, S. Frost, J. Jimenez-Suarez, A. Rodriguez-Gonzalez, P. Fernandez-Aroca, S. Sabater, I. Andres, C. Garnes-Garcia, B. Belandia, F. J. Cimas, D. Villar, M. J. Ruiz-Hidalgo, R. Sanchez-Prieto

This paper shows that MAPK11 enhances radiosensitivity by promoting IR-induced senescence without affecting DNA damage response or apoptosis in cancer cells.

bioRxiv · Sep 12, 2022 · PreprintCancer Biology