Author

F. J. Zemp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

D. J. Mahoney· 3 shared A. Abdelkareem· 2 shared D. L. Senger· 2 shared N. H. Dang· 2 shared S. Morrissy· 2 shared A. Gillmor· 1 shared A. J. Lazar· 1 shared A. J. Mungall· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

D. J. Mahoney

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Author profile →

3 papers

Recent·Most cited

Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma

V. Thoppey Manoharan, A. Abdelkareem, S. Brown, A. Gillmor, C. Hall, H. Seo, K. Narta, S. Grewal, N. H. Dang, B. Y. Ahn, K. Otz, X. Lun, L. Mah, F. J. Zemp, D. J. Mahoney, , S. Morrissy

The paper uses a novel computational workflow to analyze a spatiotemporally profiled GBM xenograft cohort, identifying 15 tumor cell programs related to invasion and their prognostic significance in GBM patients.

bioRxiv · Dec 5, 2023Cancer Biology

ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97

A. Pozner, S. P. Verma, L. Li, S. Wang, J. J. Barrott, M. L. Nelson, J. S. E. Yu, G. L. Negri, S. Colborne, C. S. Hughes, J.-F. Zhu, S. L. Lambert, L. S. Carroll, K. Smith-Fry, M. G. Stewart, , K. B. Jones

This study identifies VCP/p97 as an obligate co-factor of ASPSCR1-TFE3, showing it organizes enhancer loops to drive oncogenic transcription in ASPS and RCC.

bioRxiv · Sep 29, 2023Cancer Biology

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

M. J. Johnston, A. Nikolic, N. Ninkovic, P. Guilhamon, F. M. Cavalli, S. Seaman, F. J. Zemp, J. Lee, A. Abdelkareem, K. Ellestad, A. Murison, M. M. Kushida, F. J. Coutinho, Y. Ma, A. J. Mungall, , M. Gallo

This study uses high-resolution 3D genome maps to identify CD276 as a therapeutic target in glioblastoma stem cells, showing it can suppress self-renewal.

bioRxiv · Oct 13, 2018Cancer Biology