Author

S. Grewal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 4 Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2 Research Focus:metabolism & bioenergetics· 2 Approach:statistical model· 2 Approach:deep learning· 1

Frequent Co-Authors

J. King· 4 shared D. Scholefield· 3 shared S. Ashling· 3 shared C. Yang· 2 shared C.-y. Yang· 2 shared I. King· 2 shared I. P. King· 2 shared S. Hubbart-Edwards· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersPlant Biology

J. King

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Author profile →

9 papers

Recent·Most cited

Chromosome-scale genome assembly of bread wheat's wild relative Triticum timopheevii

S. Grewal, C. Yang, D. Scholefield, S. Ashling, S. Ghosh, D. Swarbreck, J. Collins, E. Yao, T. Z. Sen, M. Wilson, L. Yant, I. P. King, J. King

This study presents a chromosome-scale genome assembly of Triticum timopheevii using PacBio HiFi and Hi-C data, revealing genomic features and relationships between wheat genomes.

bioRxiv · Jan 16, 2024 · PreprintPlant Biology

Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma

V. Thoppey Manoharan, A. Abdelkareem, S. Brown, A. Gillmor, C. Hall, H. Seo, K. Narta, S. Grewal, N. H. Dang, B. Y. Ahn, K. Otz, X. Lun, L. Mah, F. J. Zemp, D. J. Mahoney, , S. Morrissy

The paper uses a novel computational workflow to analyze a spatiotemporally profiled GBM xenograft cohort, identifying 15 tumor cell programs related to invasion and their prognostic significance in GBM patients.

bioRxiv · Dec 5, 2023Cancer Biology

A novel genetic fluorescent reporter to visualize mitochondrial nucleoids

J. O. David, J. Deng, L. Swift, M. Zaman, A. Sharma, D. Bureik, F. Padovani, A. Benedikt, F. Shahhosseini, A. Jaiswal, A. Mohan, C. Brideau, S. Grewal, K. M. Schmoller, P. Colarusso, T. E. Shutt

The paper introduces a genetic fluorescent reporter, mt-HI-NESS, to visualize mitochondrial nucleoids in live cells without affecting mtDNA replication or expression.

bioRxiv · Oct 23, 2023 · PreprintCell Biology

Identification of Fusarium Head Blight resistance in Triticum timopheevii accessions and characterisation of wheat-T. timopheevii introgression lines for enhanced resistance.

P. Nicholson, A. Steed, M. Clarke, S. Grewal, J. King, I. King, C.-y. Yang

The paper identifies FHB-resistant Triticum timopheevii accessions and shows that introgression of chromosome 3G from these accessions into wheat enhances FHB resistance.

bioRxiv · May 13, 2022 · PreprintPlant Biology

Introgression of the Triticum timopheevii genome into wheat detected by chromosome-specific KASP markers

J. King, S. Grewal, M. Othmeni, B. Coombes, C.-y. Yang, N. Walter, S. Ashling, D. Scholefield, J. Walker, S. Hubbart-Edwards, A. Hall, I. King

The paper develops chromosome-specific KASP markers to detect introgression of Triticum timopheevii genome into wheat, identifying extensive recombination with wheat genomes.

bioRxiv · May 4, 2022 · PreprintPlant Biology

Early-life hypoxia alters adult physiology and reduces stress resistance and lifespan in Drosophila

D. M. Polan, B. Lee, M. Alansari, S. Grewal

This study shows that early-life hypoxia in Drosophila reduces adult stress resistance and lifespan, with stronger effects in males.

bioRxiv · Mar 31, 2020Physiology

Rapid identification of homozygosity and site of wild relative introgressions in wheat through chromosome-specific KASP genotyping assays

S. Grewal, S. Hubbart-Edwards, C. Yang, U. Devi, L. Baker, J. Heath, S. Ashling, D. Scholefield, C. Howells, J. Yarde, P. Isaac, I. P. King, J. King

The paper develops chromosome-specific KASP assays to rapidly detect and assess homozygosity of wild relative introgressions in wheat.

bioRxiv · May 9, 2019Plant Biology

The Immune Deficiency Pathway Regulates Metabolic Homeostasis in Drosophila.

S. Davoodi, A. Galenza, A. Panteluk, R. Deshpande, M. Ferguson, S. Grewal, E. Foley

This study shows that the IMD pathway in Drosophila affects metabolic homeostasis, with mutations leading to metabolic dysregulation and altered infection responses.

bioRxiv · Dec 14, 2018Immunology

An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar

N. D. Grubaugh, K. Gangavarapu, J. Quick, N. L. Matteson, J. Goes De Jesus, B. J. Main, A. L. Tan, L. M. Paul, D. E. Brackney, S. Grewal, N. Gurfield, K. K. Van Rompay, S. Isern, S. F. Michael, L. L. Coffey, , K. G. Andersen

The paper evaluates PrimalSeq for measuring intrahost virus diversity, showing how factors like sequencing coverage and primer mismatches affect accuracy.

bioRxiv · Aug 5, 2018Evolutionary Biology