Author

S. Seaman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Abdelkareem· 1 shared A. Chiaro· 1 shared A. D. Singhi· 1 shared A. J. Mungall· 1 shared A. Murison· 1 shared A. Nikolic· 1 shared B. Gupta· 1 shared B. St Croix· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Abdelkareem

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Selective targeting of α4β7/MAdCAM-1 axis suppresses liver fibrosis by reducing proinflammatory T cell recruitment to the liver

B. Gupta, R. P. Rai, P. B. Pal, S. Chaudhary, A. Chiaro, S. Seaman, A. D. Singhi, S. P. Monga, S. S. Iyer, R. Raeman

This study shows that targeting the α4β7/MAdCAM-1 axis reduces proinflammatory T cell recruitment to the liver, thereby suppressing liver fibrosis progression in a mouse model.

bioRxiv · Feb 20, 2023 · PreprintImmunology

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

M. J. Johnston, A. Nikolic, N. Ninkovic, P. Guilhamon, F. M. Cavalli, S. Seaman, F. J. Zemp, J. Lee, A. Abdelkareem, K. Ellestad, A. Murison, M. M. Kushida, F. J. Coutinho, Y. Ma, A. J. Mungall, , M. Gallo

This study uses high-resolution 3D genome maps to identify CD276 as a therapeutic target in glioblastoma stem cells, showing it can suppress self-renewal.

bioRxiv · Oct 13, 2018Cancer Biology