R. Feil

The stress-protectant molecule trehalose mediates fluconazole tolerance in Candida glabrata

This study identifies trehalose as a mediator of fluconazole tolerance in C. glabrata by altering sterol composition, showing that trehalose deficiency reduces drug tolerance.

Direct and indirect responses of the Arabidopsis transcriptome to an induced increase in trehalose 6-phosphate

An induced increase in trehalose 6-phosphate levels affects gene expression directly by inhibiting SnRK1 and indirectly through changes in sucrose levels, impacting growth, metabolism, and signaling pathways.

The transcription factor bZIP11 acts antagonistically with trehalose 6-phosphate to inhibit shoot branching

The paper identifies bZIP11 as a transcription factor that inhibits shoot branching in Arabidopsis by acting antagonistically with trehalose 6-phosphate.

S1 basic leucine zipper transcription factors shape plant architecture by controlling C/N partitioning to apical and lateral organs

This study identifies S1-bZIP transcription factors as regulators of plant architecture by controlling carbon and nitrogen partitioning between apical and lateral organs.

Role of the NO-GC/cGMP signaling pathway in platelet biomechanics

This study investigates the NO-GC/cGMP pathway's role in platelet biomechanics, showing that stimulators reduce cellular stiffness and activation.

Sugar signaling modulates SHOOT MERISTEMLESS expression and meristem function in Arabidopsis

This study shows that sugar signals regulate SHOOT MERISTEMLESS (STM) protein levels and meristem function in Arabidopsis by modulating SnRK1 activity.

Diel fluctuations in in-vivo SnRK1 activity in Arabidopsis rosettes during light-dark cycles

The paper measures in-vivo SnRK1 activity in Arabidopsis during light-dark cycles and finds it peaks at night and is influenced by metabolic regulators like Tre6P and glucose 6-phosphate.

Operation of Carbon-Concentrating Mechanisms in Cyanobacteria and Algae requires altered poising of the Calvin-Benson cycle

The paper compares Calvin-Benson cycle metabolite profiles in cyanobacteria and algae with terrestrial plants, finding distinct patterns suggesting the operation of carbon-concentrating mechanisms.

The Arabidopsis transcription factor NLP2 regulates early nitrate responses and integrates nitrate assimilation with energy and carbon skeleton supply

The paper identifies NLP2 as a key transcription factor regulating early nitrate responses and linking nitrate assimilation with carbon and energy metabolism in Arabidopsis.

Optogenetic manipulation of cGMP highlights PDE5 as the predominant cGMP-hydrolyzing PDE in megakaryocytes

The paper uses optogenetics to manipulate cGMP levels in megakaryocytes and identifies PDE5 as the main enzyme regulating cGMP.

Singlet oxygen-induced signalling depends on the metabolic status of the Chlamydomonas cell

This study identifies TSPP1 as a key enzyme in Chlamydomonas metabolism, showing that its absence alters 1O2-induced chloroplast retrograde signalling through metabolic intermediates.

Energy status-promoted growth and development of Arabidopsis require copper deficiency response transcriptional regulator SPL7

This study shows that SPL7 regulates energy status-promoted growth and development in Arabidopsis by modulating copper deficiency responses and sugar signaling.

Recruitment of an ancient branching program to suppress carpel development in maize flowers

The paper identifies a genetic interaction between GT1 and RA3 in maize, showing their roles in suppressing carpel development and inflorescence branching through an ancient developmental program.

The pathway of starch synthesis in Arabidopsis thaliana leaves

The paper resolves a 20-year controversy by showing that ADPG pyrophosphorylase in chloroplasts, not sucrose synthase in the cytosol, is the primary source of ADPG for starch synthesis in Arabidopsis leaves.

The role of trehalose 6-phosphate in shoot branching - local and non-local effects on axillary bud outgrowth in arabidopsis rosettes

This study investigates the role of Tre6P in shoot branching by manipulating its levels in axillary buds and vascular tissues, showing both local and systemic effects on branching via FT.

Differences in berry primary and secondary metabolisms identified by transcriptomic and metabolic profiling of two table grape color somatic variants

The paper compares transcriptomic and metabolic profiles of two table grape cultivars with different berry skin colors, identifying differences in flavonoid and primary metabolite composition and gene expression.

Proteomic and metabolomic profiling underlines the stage- and time-dependent effects of high temperature on grape berry metabolism

This study examines how high temperatures affect grape berry metabolism at different developmental stages using proteomic and metabolomic analyses, identifying key proteins and metabolic changes linked to heat stress.

Phytochrome light receptors control metabolic flux, and their action during seedling development sets the trajectory for biomass production

This study shows that phytochromes regulate metabolic flux and biomass production by controlling glucose-starch balance and carbon allocation during seedling development.

Trehalose 6-phosphate Controls Seed Filling by Inducing Auxin Biosynthesis

This study shows that trehalose 6-phosphate promotes seed filling in pea by inducing auxin biosynthesis, leading to increased starch production and seed size.