Author

L. T. Bui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Plant Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Assay:scRNA-seq· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Organism:Arabidopsis· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

A. J. Gutierrez· 4 shared C. J. Taylor· 3 shared J. A. Kropski· 3 shared A. C. Habermann· 2 shared B. Giuntoli· 2 shared F. Licausi· 2 shared I. O. Rosas· 2 shared J. C. Schupp· 2 shared

Activity by Year

2018-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersCell Biology

A. J. Gutierrez

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

An integrated cell atlas of the human lung in health and disease

L. Sikkema, D. C. Strobl, L. Zappia, E. Madissoon, N. S. Markov, L.-E. Zaragosi, M. Ansari, M.-J. Arguel, L. Apperloo, C. Becavin, M. Berg, E. Chichelnitskiy, M.-i. Chung, A. Collin, A. C. Gay, , K. Travaglini

The paper integrates 46 single-cell datasets to create the Human Lung Cell Atlas, improving cell annotation and uncovering gene modules linked to demographics and anatomy.

bioRxiv · Mar 10, 2022Cell Biology

Single-cell transcriptomic assessment of cellular phenotype stability in human precision-cut lung slices

N. I. Winters, C. J. Taylor, C. S. Jetter, J. E. Camarata, A. J. Gutierrez, L. T. Bui, J. J. Gokey, M. Bacchetta, N. E. Banovich, J. M. S. Sucre, J. A. Kropski

The paper compares single-cell transcriptomic profiles of human PCLS after five days of culture to freshly isolated lung tissue, finding changes in endothelial and alveolar epithelial cell programs but stable immune cell profiles.

bioRxiv · Aug 19, 2021 · PreprintCell Biology

Integrated Single Cell Atlas of Endothelial Cells of the Human Lung

J. C. Schupp, T. S. Adams, C. Cosme, M. S. Brickman Raredon, N. Omote, S. Poli, K.-A. Rose, E. Manning, M. Sauler, G. DeIuliis, F. Ahangari, N. Neumark, Y. Yuan, A. C. Habermann, A. J. Gutierrez, , N. Kaminski

The paper reanalyzes six scRNA-seq datasets to create a comprehensive reference atlas of human lung endothelial cells, identifying new subpopulations and confirming their conservation in mice.

bioRxiv · Oct 21, 2020Cell Biology

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

L. T. Bui, N. I. Winters, M.-I. Chung, C. Joseph, A. J. Gutierrez, A. C. Habermann, T. S. Adams, J. C. Schupp, S. Poli, L. M. Peter, C. J. Taylor, J. B. Blackburn, B. W. Richmond, A. G. Nicholson, D. Rassl, , Human Cell Atlas Lung Biological Network

The paper analyzes single-cell transcriptomes from healthy and chronic lung disease lungs to identify gene expression programs linked to SARS-CoV-2 entry and severity.

bioRxiv · Oct 20, 2020Cell Biology

Acquisition of hypoxia inducibility by oxygen sensing N-terminal cysteine oxidase in spermatophytes

D. A. Weits, L. Zhou, B. Giuntoli, L. Dalle Carbonare, S. Iacopino, L. Piccinini, V. Shukla, L. T. Bui, G. Novi, J. T. van Dongen, F. Licausi

The paper identifies two types of plant cysteine oxidases (PCOs) and shows that both are required to regulate the anaerobic response in Arabidopsis, with B-type PCOs acquiring hypoxia inducibility in spermatophytes.

bioRxiv · Jun 24, 2020Plant Biology

Differential submergence tolerance between juvenile and adult Arabidopsis plants involves the ANAC017 transcription factor

L. T. Bui, V. Shukla, F. M. Giorgi, A. Trivellini, P. Perata, F. Licausi, B. Giuntoli

This study identifies ANAC017 as a transcription factor that modulates submergence tolerance in Arabidopsis by integrating stress responses with developmental programs through epigenetic regulation.

bioRxiv · Feb 12, 2020Plant Biology

Evolution of developmental plasticity by opposing dosage of signalling-modifying enzymes

L. T. Bui, N. A. Ivers, E. J. Ragsdale

The paper shows how dosage changes of two enzymes, SEUD-1 and its counterpart, control polyphenism in Pristionchus pacificus by altering the threshold for morph development.

bioRxiv · May 21, 2018Evolutionary Biology