Spatial-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density
A. Ahmed-Cox, E. Pandzic, S. T. Johnston, C. Heu, J. B. McGhee, F. M. Mansfeld, E. J. Crampin, T. P. Davis, R. M. Whan, M. Kavallaris
This paper develops a platform to analyze nanoparticle uptake in 3D tumor spheroids, showing uptake inversely relates to particle size and varies with cell type and spheroid density.
bioRxiv · Oct 26, 2021 · PreprintBioengineering