M. Kavallaris

A 3D bioprintable hydrogel with tuneable stiffness for exploring cells encapsulated in matrices of differing stiffnesses

This study develops a tunable 3D bioprintable hydrogel to investigate how matrix stiffness and biological motifs affect cell behavior.

βIII-Tubulin is a Brake on Extrinsic Cell-Death in Pancreatic Cancer

This study identifies βIII-tubulin as a suppressor of extrinsic apoptosis in pancreatic cancer, showing that its silencing enhances sensitivity to death signals and reduces tumor progression.

A high-throughput 3D bioprinted cancer cell migration and invasion model with versatile and broad biological applicability

This paper develops a high-throughput 3D bioprinted model for studying cancer cell migration and invasion, enabling real-time analysis and drug screening.

Spatial-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density

This paper develops a platform to analyze nanoparticle uptake in 3D tumor spheroids, showing uptake inversely relates to particle size and varies with cell type and spheroid density.

A covalently crosslinked bioink for multi-materials drop-on-demand 3D bioprinting of three-dimensional cell cultures

This paper develops a covalently crosslinked bioink and a drop-on-demand 3D bioprinting platform to rapidly create complex 3D cell cultures with multiple hydrogel environments.

Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine.

This study reprograms human adipocytes into induced multipotent stem cells using PDGF-AB and 5-Azacytidine, showing their ability to regenerate tissues without ectopic growth.

Precise, high-throughput production of multicellular spheroids with a bespoke 3D bioprinter

This paper develops a 3D bioprinter for high-throughput production of multicellular spheroids and demonstrates its use in drug screening with doxorubicin.