Author

E. J. Crampin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. T. Johnston· 3 shared A. Ahmed-Cox· 1 shared A. Saito· 1 shared A. Tilunaite· 1 shared B. D. Gulbransen· 1 shared C. Heu· 1 shared C. J. Nowell· 1 shared C. Soeller· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersPhysiology

S. T. Johnston

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TRPV4 is expressed by enteric glia and muscularis macrophages of the colon but does not play a prominent role in colonic motility

P. Rajasekhar, S. E. Carbone, S. T. Johnston, C. J. Nowell, L. Wiklendt, E. J. Crampin, Y. She, J. J. DiCello, A. Saito, L. Sorensen, T. Nguyen, K. M. Lee, J. A. Hamilton, S. K. King, E. M. Eriksson, , D. P. Poole

This paper identifies TRPV4-expressing cell types in the colon and shows limited involvement of TRPV4 in colonic motility.

bioRxiv · Jan 9, 2024 · PreprintPhysiology

Spatial-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density

A. Ahmed-Cox, E. Pandzic, S. T. Johnston, C. Heu, J. B. McGhee, F. M. Mansfeld, E. J. Crampin, T. P. Davis, R. M. Whan, M. Kavallaris

This paper develops a platform to analyze nanoparticle uptake in 3D tumor spheroids, showing uptake inversely relates to particle size and varies with cell type and spheroid density.

bioRxiv · Oct 26, 2021 · PreprintBioengineering

Hierarchical semantic composition of biosimulation models using bond graphs

N. Shahidi, M. Pan, S. Safaei, K. Tran, E. J. Crampin, D. P. Nickerson

This paper introduces a method to compose biosimulation models using bond graphs and semantic annotations, demonstrating it on a human arterial circulation model to improve modularity and physical consistency.

bioRxiv · Mar 9, 2021Bioengineering

IP3R activity increases frequency of RyR-mediated sparks by elevating dyadic Ca2+

J. Chung, A. Tilunaite, D. Ladd, H. Hunt, C. Soeller, E. J. Crampin, S. Johnston, H. Roderick, V. Rajagopal

The paper develops a mathematical model to show IP3R activity increases Ca2+ sparks by raising dyadic Ca2+ levels, which sensitizes RyRs but reduces JSR Ca2+ availability.

bioRxiv · Aug 13, 2020Biophysics

Isolating the sources of heterogeneity in nanoparticle-cell interactions

S. T. Johnston, M. Faria, E. J. Crampin

This paper presents a mathematical framework to isolate factors causing heterogeneity in nanoparticle-cell interactions and demonstrates three key factors explaining experimental variation.

bioRxiv · Oct 24, 2019 · PreprintBiophysics