Author

F. Mechta-Grigoriou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Y. Kieffer· 2 shared A. Herbette· 1 shared A. Latouche· 1 shared a. mencattini· 1 shared A. Nicolas· 1 shared A. Santi· 1 shared A. Simon· 1 shared A. Vincent-Salomon· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Y. Kieffer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ex vivo quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

i. veith, a. mencattini, m. nurmik, i. damei, c. lansche, s. brosseau, g. gropplero, s. corgnac, j. filippi, n. pote, p. mordant, j. tosello, c. sedlik, e. piaggio, n. girard, , M. C. PARRINI

This study develops and validates lung-tumor-on-chip platforms to measure ex vivo anti-PD-1 treatment effects on T-cell activity using live imaging and image analysis.

bioRxiv · Jun 21, 2023 · PreprintCancer Biology

Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function

A. Santi, E. J. Kay, L. J. Neilson, L. McGarry, S. Lilla, M. Mullin, N. R. Paul, F. Fercoq, G. Koulouras, G. Rodriguez-Blanco, D. Athineos, S. Mason, M. Hughes, Y. Kieffer, C. Nixon, , S. Zanivan

CAFs with a myofibroblastic-like phenotype transfer proteins to ECs, including plasma membrane receptors, through matrix-bound EVs.

bioRxiv · Jan 13, 2023 · PreprintCancer Biology

Low centrosome numbers correlate with higher aggressivity in ovarian cancer

J.-P. Morretton, A. Simon, A. Herbette, J. Barbazan, C. Perez-Gonzalez, C. Cosson, B. Mboup, A. Latouche, T. Popova, Y. Kieffer, P. Gestraud, G. Bataillon, V. Becette, D. Meseure, A. Nicolas, , R. Basto

The paper analyzes centrosome numbers in ovarian cancers and finds that low centrosome numbers correlate with poor patient survival and mesenchymal subgroup enrichment.

bioRxiv · Jan 4, 2022 · PreprintCancer Biology