The Novel Mnk1/2 Degrader VNLG-152 Potently Inhibits TNBC Tumor Growth and Metastasis
V. C. O. Njar, S. Ramalingam, V. Ramamurthy, L. K. Gediya, F. N. Murigi, P. Purushottamachar, W. Huang, M. A. Kane, E. Y. Choi, R. G. Lapidus, T. S. Vasaitis, Y. Zhang
This study identifies VNLG-152R, a Mnk1/2 degrader, as a potent inhibitor of TNBC tumor growth and metastasis with minimal toxicity.
bioRxiv · Oct 9, 2018Cancer Biology