Author

E. Y. Choi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

A. Amor-Coarasa· 1 shared A. Nikolopoulou· 1 shared B. S. Slusher· 1 shared C. Kratochwil· 1 shared D. Abou· 1 shared D. L. Thorek· 1 shared F. N. Murigi· 1 shared J. Babich· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Amor-Coarasa

Mutual co-authors in cluster

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2 papers

Recent·Most cited

JHU-2545 Selectively Shields Salivary Glands and Kidneys during PSMA-Targeted Radiotherapy

M. T. Nedelcovych, R. P. Dash, Y. Wu, E. Y. Choi, R. S. Lapidus, P. Majer, D. Abou, M.-F. Penet, A. Nikolopoulou, A. Amor-Coarasa, J. Babich, D. L. Thorek, R. Rais, C. Kratochwil, B. S. Slusher

This paper describes the development of JHU-2545, a prodrug that selectively shields salivary glands and kidneys from PSMA-targeted radiotherapy, improving safety without affecting tumor uptake.

bioRxiv · Feb 15, 2019 · PreprintPharmacology & Toxicology

The Novel Mnk1/2 Degrader VNLG-152 Potently Inhibits TNBC Tumor Growth and Metastasis

V. C. O. Njar, S. Ramalingam, V. Ramamurthy, L. K. Gediya, F. N. Murigi, P. Purushottamachar, W. Huang, M. A. Kane, E. Y. Choi, R. G. Lapidus, T. S. Vasaitis, Y. Zhang

This study identifies VNLG-152R, a Mnk1/2 degrader, as a potent inhibitor of TNBC tumor growth and metastasis with minimal toxicity.

bioRxiv · Oct 9, 2018Cancer Biology