Author

C. B. Mulholland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

H. Leonhardt· 3 shared S. Bultmann· 2 shared A. Nishiyama· 1 shared D. Haxholli· 1 shared E. Hildebrand· 1 shared E. Parsa· 1 shared E.-M. Eckl· 1 shared F. R. Traube· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

H. Leonhardt

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Author profile →

3 papers

Recent·Most cited

Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger

K. Hata, N. Kobayashi, K. Sugimura, W. Qin, D. Haxholli, Y. Chiba, S. Yoshimi, G. Hayashi, H. Onoda, T. Ikegami, C. B. Mulholland, A. Nishiyama, M. Nakanishi, H. Leonhardt, T. Konuma, K. Arita

This study determines the structure of the mouse UHRF1 PHD domain complexed with DPPA3, revealing how DPPA3 inhibits UHRF1 chromatin localization through unique interactions.

bioRxiv · Jun 14, 2022Biochemistry

SPATIAL ORGANIZATION OF TRANSCRIBED EUKARYOTIC GENES

S. Leidescher, J. Ribisel, S. Ullrich, Y. Feodorova, E. Hildebrand, S. Bultmann, S. Link, K. Thanisch, C. B. Mulholland, J. Dekker, H. Leonhardt, L. Mirny, I. Solovei

This study investigates how transcription shapes genome spatial organization by analyzing long highly expressed genes and demonstrating the formation of transcription loops with polymerases and nascent RNAs.

bioRxiv · May 20, 2020Cell Biology

Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency

C. B. Mulholland, F. R. Traube, E. Parsa, E.-M. Eckl, M. Schoenung, M. Modic, M. D. Bartoschek, P. Stolz, J. Ryan, T. Carell, H. Leonhardt, S. Bultmann

The paper compares TET1 and TET2 contributions to cytosine oxidation during naive to primed pluripotency transition, finding distinct and differentiation-dependent roles in 5hmC and 5fC formation.

bioRxiv · Mar 13, 2018Cell Biology