Manipulation of IRE1-dependent MAPK signaling by a Vibrio agonist-antagonist effector pair
N. J. De Nisco, A. K. Casey, M. Kanchwala, A. E. Lafrance, F. S. Coskun, L. N. Kinch, N. V. Grishin, C. Xing, K. Orth
This paper shows how Vibrio parahaemolyticus uses two effectors, VopQ and VopS, to manipulate host signaling by first inducing pro-survival responses and then triggering cell death.
bioRxiv · Sep 1, 2020Microbiology