L. N. Kinch

Molecular Determinants for Differential Activation of the Vibrio parahaemolyticus Bile Acid Receptor

This study identifies molecular determinants for differential activation of the Vibrio parahaemolyticus bile acid receptor by showing how specific bile acids bind to the VtrA/VtrC complex and influence pathogenic gene expression.

Enzymatic Specificity of Conserved Rho GTPase Deamidases Promotes Invasion of Vibrio parahaemolyticus at the Expense of Infection

This study shows that CNF1 enhances V. parahaemolyticus invasion but fails to complete infection, while VopC allows efficient invasion and infection completion, highlighting the importance of enzymatic specificity in bacterial pathogenesis.

Co-Component Signal Transduction Systems: fast-evolving virulence regulation cassettes discovered in enteric bacteria

The paper identifies fast-evolving co-component signal transduction systems in enteric bacteria using domain organization and machine learning-based fold predictions.

Manipulation of IRE1-dependent MAPK signaling by a Vibrio agonist-antagonist effector pair

This paper shows how Vibrio parahaemolyticus uses two effectors, VopQ and VopS, to manipulate host signaling by first inducing pro-survival responses and then triggering cell death.

Genomics reveals the origins of ancient specimens

This study uses genomics to determine the geographical origins of ancient butterfly specimens, resolving long-standing taxonomic disputes and demonstrating the utility of ancient DNA in species delineation.