Author

A. K. Casey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:Drosophila· 1

Frequent Co-Authors

K. Orth· 3 shared H. A. Fields· 2 shared A. Blevins· 1 shared A. Cox· 1 shared A. E. Lafrance· 1 shared A. Moehlman· 1 shared B. Gulen· 1 shared B. M. Evers· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersPhysiology

K. Orth

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Author profile →

3 papers

Recent·Most cited

FicD regulates adaptation to the unfolded protein response in the murine liver.

A. K. Casey, N. M. Stewart, N. Zaidi, H. A. Gray, A. Cox, H. A. Fields, K. Orth

This study shows FicD regulates UPR responses in the murine liver during mild stress but not chronic or acute UPR induction.

bioRxiv · Apr 15, 2024Physiology

Fic-mediated AMPylation tempers the Unfolded Protein Response during physiological stress

A. K. Casey, H. F. Gray, S. Chimalapati, G. Hernandez, A. Moehlman, N. Stewart, H. A. Fields, B. Gulen, K. A. Servage, K. Stefanius, A. Blevins, E. Daoud, B. M. Evers, H. Kramer, K. Orth

This study shows that Fic-mediated AMPylation regulates the UPR response in the pancreas during stress, preventing excessive inflammation and damage.

bioRxiv · Apr 27, 2022Physiology

Manipulation of IRE1-dependent MAPK signaling by a Vibrio agonist-antagonist effector pair

N. J. De Nisco, A. K. Casey, M. Kanchwala, A. E. Lafrance, F. S. Coskun, L. N. Kinch, N. V. Grishin, C. Xing, K. Orth

This paper shows how Vibrio parahaemolyticus uses two effectors, VopQ and VopS, to manipulate host signaling by first inducing pro-survival responses and then triggering cell death.

bioRxiv · Sep 1, 2020Microbiology