Author

A. E. Lafrance

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

K. Orth· 2 shared L. N. Kinch· 2 shared A. K. Casey· 1 shared C. Xing· 1 shared F. S. Coskun· 1 shared K. G. Kaval· 1 shared M. Kanchwala· 1 shared N. J. De Nisco· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

K. Orth

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Enzymatic Specificity of Conserved Rho GTPase Deamidases Promotes Invasion of Vibrio parahaemolyticus at the Expense of Infection

K. Orth, A. E. Lafrance, S. Chimalapati, N. M. Garcia-Rodriguez, L. N. Kinch, K. G. Kaval

This study shows that CNF1 enhances V. parahaemolyticus invasion but fails to complete infection, while VopC allows efficient invasion and infection completion, highlighting the importance of enzymatic specificity in bacterial pathogenesis.

bioRxiv · Jun 13, 2022Microbiology

Manipulation of IRE1-dependent MAPK signaling by a Vibrio agonist-antagonist effector pair

N. J. De Nisco, A. K. Casey, M. Kanchwala, A. E. Lafrance, F. S. Coskun, L. N. Kinch, N. V. Grishin, C. Xing, K. Orth

This paper shows how Vibrio parahaemolyticus uses two effectors, VopQ and VopS, to manipulate host signaling by first inducing pro-survival responses and then triggering cell death.

bioRxiv · Sep 1, 2020Microbiology