Rapid evolution drives the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection
R. Wheatley, J. Diaz Caballero, N. Kapel, A. Quinn, E. del Barrio-Tofino, C. Lopez-Causape, J. Hedge, G. Torrens, T. Van der Schalk, B. Britto Xavier, F. Fernandez-Cuenca, A. Arenzana, C. Recanatini, L. Timbermont, F. Sifakis, , C. MacLean
The paper tracks the rapid evolution of carbapenem resistance in P. aeruginosa during an acute infection, showing resistance rise and fall due to antibiotic treatment.
bioRxiv · Aug 10, 2020Evolutionary Biology