Author

C. Lopez-Causape

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:whole-genome sequencing· 3 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Oliver· 5 shared A. Quinn· 2 shared A. Ruzin· 2 shared B. Britto Xavier· 2 shared C. Recanatini· 2 shared J. Diaz Caballero· 2 shared J. Kluytmans· 2 shared L. Timbermont· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

A. Oliver

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Involvement of Pf-like phages in resistance to phage infection in clinical isolates of P. aeruginosa from cystic fibrosis patients

L. Blasco, A. Barrio-Pujante, C. Lopez-Causape, L. Arman, I. Bleriot, O. Pacios, L. Fernandez-Garcia, C. Ortiz-Cartagena, C. Ibarguren-Quiles, R. Canton, A. Oliver, M. Tomas

The paper identifies 12 new Pf-like phages in P. aeruginosa clinical isolates and links their presence to resistance against phage infection through novel anti-phage defence systems.

bioRxiv · May 3, 2024 · PreprintMicrobiology

Elucidating effects of single and multiple resistance mechanisms on bacterial response to meropenem by quantitative and systems pharmacology modeling and population genomics

D. T. Fuhs, S. Cortes-Lara, J. R. Tait, K. E. Rogers, C. Lopez-Causape, W. L. Lee, D. M. Shackleford, R. L. Nation, A. Oliver, C. B. Landersdorfer

This study uses QSP modeling and population genomics to show that baseline resistance mechanisms in Pseudomonas aeruginosa affect bacterial killing and resistance emergence, and that fT>MIC cannot predict these outcomes.

bioRxiv · Feb 17, 2024 · PreprintMicrobiology

Polyclonal pathogen populations accelerate the evolution of antibiotic resistance in patients

J. Diaz Caballero, R. M. Wheatley, N. Kapel, C. Lopez-Causape, T. Van der Schalk, A. Quinn, C. Recanatini, B. Britto Xavier, L. Timbermont, J. Kluytmans, A. Ruzin, M. Esser, S. Malhotra-Kumar, A. Oliver, R. C. MacLean, WP3A working group

Antibiotic resistance evolves quickly in patients colonized by polyclonal pathogen populations.

bioRxiv · Dec 10, 2021 · PreprintEvolutionary Biology

Whole genome sequencing evidences higher rates of relapse in Clostridioides difficile infection caused by PCR ribotype 106

L. Suarez, C. Lopez-Causape, A. Oliver, A. Mena

This study uses whole genome sequencing to show that recurrent Clostridioides difficile infections caused by ribotype 106 are mainly due to relapses from the same strain rather than reinfections.

bioRxiv · Mar 23, 2021 · PreprintMicrobiology

Rapid evolution drives the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection

R. Wheatley, J. Diaz Caballero, N. Kapel, A. Quinn, E. del Barrio-Tofino, C. Lopez-Causape, J. Hedge, G. Torrens, T. Van der Schalk, B. Britto Xavier, F. Fernandez-Cuenca, A. Arenzana, C. Recanatini, L. Timbermont, F. Sifakis, , C. MacLean

The paper tracks the rapid evolution of carbapenem resistance in P. aeruginosa during an acute infection, showing resistance rise and fall due to antibiotic treatment.

bioRxiv · Aug 10, 2020Evolutionary Biology