Author

P.-J. Bordignon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Organism:E. coli· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

E. Meunier· 4 shared R. Planes· 4 shared E. Eren· 3 shared S. Bagayoko· 3 shared A. Coste· 2 shared A. Hessel· 2 shared C. Cougoule· 2 shared E. Oswald· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

E. Meunier

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

HlyF, an underestimated virulence factor of uropathogenic Escherichia coli

C. V. Chagneau, D. Payros, A. Goman, C. Goursat, L. David, M. Okuno, P.-J. Bordignon, C. Seguy, C. Massip, P. Branchu, Y. Ogura, J.-P. Nougayrede, M. Marenda, E. Oswald

The paper identifies HlyF as a virulence factor in UPEC strains associated with severe UTIs and urosepsis, showing its link to plasmid-mediated virulence and antimicrobial resistance.

bioRxiv · Apr 27, 2023 · PreprintMicrobiology

Outer membrane vesicles produced by pathogenic strains of Escherichia coli block autophagic flux and exacerbate inflammasome activation

L. DAVID, F. Taieb, M. Penary, P.-J. Bordignon, R. Planes, S. Bagayoko, V. Duplan-Eche, E. Meunier, E. Oswald

The paper shows that OMVs from pathogenic E. coli block autophagic flux and enhance inflammasome activation, contributing to disease severity.

bioRxiv · Apr 20, 2021Microbiology

Phospholipid peroxidation fuels ExoU phospholipase-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology

S. Bagayoko, S.-A. Leon-Icaza, M. Pinilla, A. Hessel, K. Santoni, P.-J. Bordignon, F. Moreau, E. Eren, A. Boyance, E. Naser, L. Lefevre, C. Berrone, N. Iacobachvili, A. Metais, Y. Rombouts, , E. Meunier

This study identifies phospholipid peroxidation as a mechanism enhancing ExoU phospholipase activity, leading to cell necrosis and supporting Pseudomonas aeruginosa pathogenesis.

bioRxiv · Feb 17, 2021Immunology

Irgm2 and Gate-16 cooperatively dampen targeting of caspase-11 to Gram-negative bacterial products

E. Eren, R. Planes, S. Bagayoko, P.-J. Bordignon, K. Chaoui, A. Hessel, K. Santoni, M. Pinilla, O. Schiltz, J. C. Howard, M. Yamamoto, E. Meunier

This study identifies Irgm2 and Gate-16 as cooperative regulators that dampen non-canonical inflammasome activation by reducing caspase-11 targeting to intracellular bacteria.

bioRxiv · Mar 6, 2020Immunology

Type-3 Secretion System-induced pyroptosis protects Pseudomonas against cell-autonomous immunity

E. Eren, R. Planes, J. M. Buyck, P.-J. Bordignon, A. Colom, O. Cunrath, R. F. Dreier, J. C. Santos, V. Duplan-Eche, E. Näser, A. Peixoto, D. Bumann, C. Cougoule, A. Coste, O. Neyrolles, , E. Meunier

This study shows that Pseudomonas aeruginosa uses its Type-3 Secretion System to induce macrophage pyroptosis, escaping immune trapping, while T3SS-deficient strains are captured by inflammasome-mediated immunity.

bioRxiv · May 28, 2019 · PreprintImmunology