SARS-CoV-2-Triggered Mast Cell Rapid Degranulation Induces Alveolar Epithelial Inflammation and Lung Injury
M.-L. Wu, F.-L. Liu, J. Sun, X. Li, X.-Y. He, H.-Y. Zheng, R.-J. Pei, H. Sun, Y.-H. Zhou, Q.-H. Yan, C.-X. Wu, L. Chen, G.-Y. Yu, J. Chang, X. Jin, , J.-H. Wang
This paper shows that SARS-CoV-2 triggers mast cell degranulation, leading to alveolar epithelial inflammation and lung injury, and that MC stabilizers can reduce these effects.
bioRxiv · Jun 24, 2021Microbiology