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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
J.-H. Wang, Z. Gong, X. Dong, S.-Q. Liu, Y.-L. Tang, X. Lei, C. Tang, M.-Q. Dong
This study compares DOPA2 and DSS cross-linkers, finding that faster cross-linking favors the stereospecific complex over encounter complexes in transient protein interactions.
bioRxiv · Jun 6, 2022 · PreprintBiochemistry
C. Zhang, Y.-X. Fang, X. Yin, H. Lai, Z. Kuang, T. Zhang, X.-P. Xu, G. Wegener, J.-H. Wang, X. Dong
This study identifies fermentation of macromolecules as the dominant energy source for microorganisms in gas hydrate-bearing subseafloor sediments.
bioRxiv · May 19, 2022Microbiology
S. Yang, G. Hiotis, Y. Wang, J. Chen, J.-h. Wang, M. Kim, E. L. Reinherz, T. Walz
The paper investigates HIV-1 spike protein dynamics using cryo-EM and simulations, showing how tilting exposes the MPER to antibody attack and alters membrane fusion.
bioRxiv · May 9, 2022Biophysics
L. Shi, H. Ma, H. Zhao, M. Ma, J. Wang, R. Kong, Z. Li, R. Ma, J.-H. Wang, S. Wu, M.-Q. Dong, Z. Li
This study identifies the EMC complex's role in regulating intestinal stem cell proliferation via the Hippo pathway in Drosophila, showing its negative regulation and evolutionary conservation.
bioRxiv · Jan 25, 2022 · PreprintCell Biology
M.-L. Wu, F.-L. Liu, J. Sun, X. Li, X.-Y. He, H.-Y. Zheng, R.-J. Pei, H. Sun, Y.-H. Zhou, Q.-H. Yan, C.-X. Wu, L. Chen, G.-Y. Yu, J. Chang, X. Jin, , J.-H. Wang
This paper shows that SARS-CoV-2 triggers mast cell degranulation, leading to alveolar epithelial inflammation and lung injury, and that MC stabilizers can reduce these effects.
bioRxiv · Jun 24, 2021Microbiology
F.-L. Lin, J.-H. Wang, J. Chen, L. Zhu, Y.-F. Chuang, L. Tu, C. Ma, S. Lama, D. Ling, R. C.-B. Wong, A. W. Hewitt, C.-L. Tseng, B. V. Bui, P. van Wijngaarden, G. J. Dusting, , G.-S. Liu
This study investigates TAK1's role in retinal neovascularization and shows that inhibiting TAK1 reduces aberrant angiogenesis in a rat model.
bioRxiv · Jan 29, 2021Biochemistry
H.-C. Yang, C.-h. Chen, J.-H. Wang, H.-C. Liao, C.-T. Yang, C.-W. Chen, Y.-C. Lin, C.-H. Kao, J. C. Liao
This study analyzes the genomic, geographic, and temporal distribution of SARS-CoV-2 mutations using 1,932 genomes, identifying six phylogenetic clusters and a positive correlation between mutation count and case fatality.
Proceedings of the National Academy of Sciences · Nov 12, 2020Peer-reviewedMicrobiology
J.-H. Wang, Y.-L. Tang, R. Jain, F. Xiao, Z. Gong, Y. Zhou, D. Tan, Q. Li, X. Dong, S.-Q. Liu, C. Tang, N. Huang, K. Ye, M.-Q. Dong, X. Lei
This study introduces a fast lysine cross-linker DOPA for mass spectrometry analyses, showing it enables rapid protein cross-linking and captures dynamic conformational changes and weak protein-protein interactions.
bioRxiv · Nov 5, 2020 · PreprintBiochemistry
Z. Li, D. Pan, G. Wei, W. Pi, J.-H. Wang, Y. Peng, L. Zhang, Y. Wang, C. R. J. Hubert, X. Dong
The paper analyzes viral diversity in deep sea cold seep sediments, finding high endemism and links to microbial hosts and biogeochemical cycling.
bioRxiv · Sep 8, 2020Microbiology
L. Lv, P. Chen, L. Cao, Y. Li, Z. Zeng, Y. Cui, Q. Wu, J. Li, J.-H. Wang, M.-Q. Dong, X. Qi, T. Han
This paper discovers a molecular glue, HQ461, that promotes CDK12-DDB1 interaction, leading to Cyclin K degradation and cell death.
bioRxiv · Jun 10, 2020Biochemistry
F. Li, K. Wing, J.-H. Wang, C. D. Luu, J. A. Bender, J. Chen, Q. Wang, Q. Lu, M. T. N. T. Tran, K. M. Young, R. C. Wong, A. Pebay, A. L. Cook, S. S. Hung, G.-S. Liu, A. W. Hewitt
This study compares CRISPR/Cas endonucleases for in vivo retinal gene editing and finds SpCas9 delivered via AAV7m8 achieves the highest knockout efficacy.
bioRxiv · Jun 9, 2020Bioengineering