Author

Flavia De Carlo

Centre Hospitalier Universitaire Vaudois

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

David BarrasiD· 3 shared Denarda Dangaj LanitiiD· 3 shared George CoukosiD· 3 shared Mathieu DesbuissoniD· 3 shared Aspram MinasyaniD· 2 shared Bovannak Stewen ChapiD· 2 shared Eleonora GhisoniiD· 2 shared Fabrizio BenedettiiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

David BarrasORCID

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Author profile →

3 papers

Recent·Most cited

Actionable spatial prostanoid barriers constrain BiTE-driven adoptive T cell immunity in intact human tumors

Bovannak Stewen Chap, Tania Santoro, Paris Kosti, David Barras, Noémie Fahr, Mathieu Desbuisson, Fabrizio Benedetti, Aspram Minasyan, Asia Andreoli, E. Ghisoni, Flavia De Carlo, Khadidja Benkortbi, Apostolos Sarivalasis, Chahin Achtari, Delfyne Hastir, , Denarda Dangaj Laniti

The paper uses patient-derived explants to study BiTE-driven T cell responses in tumors, identifying the COX/PGE2 axis as a barrier to immune activation and showing COX inhibition enhances anti-tumor effects.

bioRxiv · Mar 30, 2026 · PreprintSystems Biology

Computational Inference of Metabolic Programs: A Case Study Analyzing the Effect of BRCA1 Loss

María Masid, Ioanna A. Rota, David Barras, Flavia De Carlo, Pierpaolo Ginefra, Mathieu Desbuisson, Yaquelin Ortiz-Miranda, Dmitriy Zamarin, Sohrab P. Shah, Nicola Vannini, George Coukos, Denarda Dangaj Laniti, Vassily Hatzimanikatis A

This study introduces iMSEA, a computational framework that identifies metabolic state shifts in BRCA1-deficient cancers using omics data and validates findings with experimental assays.

bioRxiv · Nov 18, 2025 · PreprintSystems Biology

Myeloid cell networks determine reinstatement of original immune environments in recurrent ovarian cancer

Eleonora Ghisoni, Fabrizio Benedetti, Aspram Minasyan, Mathieu Desbuisson, Paula Cunnea, Alizée J Grimm, Noémie Fahr, Charlotte Capt, Nicolas Rayroux, Flavia De Carlo, D. C. Gulhan, Julien Dagher, David Barras, Matteo Morotti, Juan A. Marín‐Jiménez, , Denarda Dangaj Laniti

The paper identifies immune phenotypes and myeloid cell networks in recurrent ovarian cancer that influence prognosis and immune environment reinstatement.

Cancer Cell · Jul 31, 2025Peer-reviewedImmunology